It's the latest in a series of high-profile departures from the network. Discovery Health & Fitness senior vice president Rita Mullin will serve as an interim replacement.

"Oprah's Next Chapter" interview with Joel Osteen drew 1.6 million viewers

"Oprah's Next Chapter" will debut on New Year's Day

Exit of Oprah Winfrey's best friend appears to be amicable

The Academy's annual ceremony for honorary Oscars has become an irresistible stop on the campaign trail

Competing with bridezillas, bad girls and real housewives, OWN vows to "bring light" -- even at the expense of short-term success

"Walking Dead" and its companion talk show, "Talking Dead," premiere, while Jennifer Aniston, Alicia Keys and Demi Moore take on breast cancer for Lifetime

The former Fox News host has netted 230,000 subscribers

Like Oprah and Ellen, the former CBS News anchor is sticking to tradition and lopping off her last name

Peter Tolan wears skimpy underwear, Oprah looms large...

EXCLUSIVE: From civil rights groups to Oprah Winfrey, criticism is rising at the cable giant's slow moves on its diversity pledge

The solution isn't for the network to better reflect her voice -- it's for the Queen of Talk to talk to her fans again

She exits with her most-watched episode in 18 years

Show scored 13.3 household rating in the overnight metered markets