The couple married in August 2004.
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An individual familiar with the situation told TheWrap that Lane filed for the divorce.
This was the second marriage for both "No Country for Old Men" star Brolin and "The Perfect Storm" actress Lane. Brolin had previously been married to actress Alice Adair, with whom he has two children. Lane's first marriage was to her "After the Rain" co-star Christopher Lambert. Lane and Lambert have a daughter together.