Paramount, which is co-producing with Warner Bros., had no comment.
"Interstellar" stars Matthew McConaughey, Hathaway, Jessica Chastain and Nolan favorite Michael Caine, who previously worked with the director on "Inception," "The Prestige" and the "Dark Knight" trilogy.
Story follows a heroic group of explorers who travel through a wormhole and into another dimension.
Like the other actors, details of Irwin's role are being kept under wraps, as Nolan is famously secretive.
Jonah Nolan wrote the original script, which has since been merged with one of Nolan's original sci-fi ideas. The director is also producing with Emma Thomas and Lynda Obst, while Jordan Goldberg will exec produce with Caltech physicist Kip Thorne, who serves as a technical consultant on the project.
Irwin recently starred on TNT's "Monday Mornings" and was last seen on the big screen in Vera Farmiga's directorial debut "Higher Ground." His other feature credits include "Across the Universe," "Lady in the Water," "The Manchurian Candidate" and "How the Grinch Stole Christmas." His supporting performance as Hathaway's father in Jonathan Demme's "Rachel Getting Married" earned recognition from the Chicago Film Critics Association.
Irwin is repped by Innovative Artists and Viking Entertainment.