Braff's character gets "so much bad news all at once" in his crowdfunded directorial follow-up to "Garden State"
New season will premiere in the summer
The duo will guest star as siblings and eligible bachelors on the TV Land comedy
Remini will play the recently single sister of Stuart
She will appear on the TV Land comedy's upcoming Season 3, which premieres on June 19
Estelle Harris will guest star on the comedy's third season, which begins June 19
Fran Drescher, Donald Faison and Wayne Knight will star in sitcoms about life after divorce
Alien invasion movie stars TV veterans Donald Faison, Eric Balfour, David Zayas, Scottie Thompson and Brittany Daniel