The "Late Show" host asked the tennis champion Thursday about recreating the classic Billie Jean King-Bobby Riggs "Battle of the Sexes." Men's top Brit Andy Murray continuously teases Williams about playing a modern version, she said.
But that is never going to happen.
"If I were to play Andy Murray, I would lose, 6-0, 6-0, in 5 to 6 minutes, maybe 10 minutes," Williams said.
"The men are a lot faster, they serve harder, they hit harder," she continued. "It's a completely different game."
"I'm with you," Letterman said. "When it comes to tennis, I only want to play girls."
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