While promoting her upcoming film "Red 2," Mirren offered some sage words of wisdom for Lohan, Bynes and other famous young people who've found themselves on a wayward path.
Mirren didn't mince words. The biggest favor that Lohan and Bynes can do themselves, in Mirren's estimation? Avoid cranial-rectal inversion.
"I don't know if you're allowed to say this on television: Don't be up your own bum," Mirren offered.
For those not well-versed in slang for anatomical parts, Mirren wasn't referring to vagrants.
"People get their own [bum], and you really don't need to. It's the thing of the young, and just don't do that," Mirren continued.
"She's the Man" actress Bynes has recently attracted negative attention for a series of bizarre tweets on topics such as her desire for musician Drake to commit homicide against her lady-bits.
Lohan, of course, has attracted negative attention for being Lindsay Lohan, most recently entering rehab — again — after pleading no contest to misdemeanor charges related to a June 2012 car accident.
Watch Mirren dispense some harsh truth in the video: