Pirates of the Caribbean: 2003
The franchise that made Depp -- and Disney -- very rich. "Pirates of the Caribbean 5" is scheduled for release in 2015, with Depp returning as Capt. Jack Sparrow.
The Lone Ranger: 2013
Depp plays Tonto, the Lone Ranger's trusty sidekick, in Disney's adaptation of the popular old radio serial.
Fear and Loathing in Las Vegas: 1998
The actor channels gonzo journalist Hunter S. Thompson in the adaptation of his drug-fueled escapades.
Benny and Joon: 1993
Depp's fascination with top hats began with this quirky romance, where Depp showed off Charlie Chaplin moves.
Depp plays an accountant in Jim Jarmusch's film.
Charlie and the Chocolate Factory: 2005
Depp's stylized getup in this remake turned off fans of the 1971 adaptation of the book starring Gene Wilder.
Alice in Wonderland: 2010
Depp as the Mad Hatter in what else? A distinctive chapeau.
Sweeney Todd: 2007
The actor played the killer barber with oddly graying hair.
Edward Scissorhands: 1990
Depp turned on the melancholy charm as Edward, a guy who hurts anyone he touches.
Ed Wood: 1994
The actor stars as filmmaker Ed Wood, a guy with a thing for angora sweaters.
21 Jump Street: 1987
He played an undercover cop at a hight school in the television drama that kickstarted his career and put him in the hearts of women everywhere.
The actor does a lot of cocaine in this biopic about cocaine smuggler George Jung.
Depp insisted on keeping all of the clothes from the movie to wear to the Oscars.
Cry Baby: 1990
John Waters directed Depp in this parody of teen musicals, which lampooned his pin-up image.
Dark Shadows: 2012
Depp poured on the makeup for his role as vampire Barnabas Collins in last year's misfire.
Finding Neverland: 2004
The actor got an Oscar nomination of his performance as J.M. Barrie, who wrote "Peter Pan."
From Hell: 2001
Depp plays a police inspector searching for Jack the Ripper.
Once Upon a Time in Mexico: 2003
He plays a CIA agent in Mexico in this movie.
Sleepy Hollow: 1999
Depp starred as Ichabod Crane in this adaptation of the Washington Irving story.