Ryan Reynolds Is Ben Mendelsohn’s Lucky Charm in First ‘Mississippi Grind’ Trailer (Video)

A24’s gambling road comedy opens in theaters Sept. 25

Last Updated: July 22, 2015 @ 2:19 PM

Ryan Reynolds is a good luck charm for Ben Mendelsohn in the first trailer for “Mississippi Grind.”

The A24 release follows Gerry (Mendelsohn), a gambler who can’t seem to win a bet. Down on his luck and up to his eyes in debt, he makes the acquaintance of a charismatic young poker player named Curtis (Reynolds).

The two become fast friends, with Gerry convinced that Curtis is good luck. The two set out on a roadtrip down south, hitting up every casino, dog track, and poker game they can find along the Mississippi River.

The film also stars Sienna Miller, Analeigh Tipton, and Robin Weigert. It was co-directed and co-written by Anna Boden and Ryan Fleck.

“Mississippi Grind” will debut in theaters on September 25.

Watch the trailer that debuted Wednesday.