Contrary to what the title might suggest, “Nuts!” is not about a squirrel searching for its next meal or someone losing their mind. Instead, the Sundance documentary is the fascinating story of the doctor who discovered he could implant goat testicles into men to cure impotence.

In the exclusive trailer (above), the history of Dr. John Romulus Brinkley is chronicled, and the trailer also shows off the film’s distinctive aesthetic, with animated reenactments making up more than half of the runtime.

The film is described as the mostly true story of Brinkley, an eccentric genius who built an empire with his goat-testicle impotence cure and a million-watt radio station.

Also Read: Sundance 2016: Four Female Directors Win Horizon Awards

In addition to its animated reenactments, the story is told through interviews, archival footage and one seriously unreliable narrator who traces Brinkley’s rise from poverty to celebrity and influence in 1920s America.

“Nuts!” is premiering in the U.S. Documentary Competition at the 2016 Sundance Film Festival.

Sundance 2016: 13 Breakout Stars to Watch, From Parker Sawyers to Lily-Rose Depp (Photos)

Tika Sumpter and Parker Sawyers, "Southside With You" - Richard Tanne's drama chronicles the epic first date of Barack Obama and Michelle Robinson across Chicago's South Side in the summer of 1989. This could be Sumpter's breakout feature role, and while Sawyers doesn't have a U.S. agent heading into Sundance, expect that to change quickly.
Harley Quinn Smith and Lily-Rose Depp, "Yoga Hosers" - The Colleens from Kevin Smith's "Tusk" are back in the director's follow-up, which finds the two teenage yoga enthusiasts teaming up with a legendary man-hunter to battle an ancient evil presence that threatens their party plans. The daughters of Smith and co-star Johnny Depp stole a couple scenes in "Tusk," but this is their first real opportunity to prove they can hold the screen like their fathers. Depp is already on Hollywood's radar, co-starring opposite Natalie Portman in "Planetarium" and testing for the lead in Paramount's "Looking for Alaska."
Michael Barbieri and Theo Taplitz, "Little Men" - Director Ira Sachs returns to Sundance with this film that rests on the slender shoulders of its teenage stars. The duo play best friends whose bond is tested by their parents' battle over a dress shop lease. Taplitz has done plenty of theater and creates short films in his spare time, while Barbieri is a student at the Lee Strasberg Theater and Film Institute in New York. While "Little Men" is his feature film debut, he also appears in Matt Kazman's short film "Killer," which premieres at Sundance.
Lucas Hedges, "Manchester By the Sea" - You probably remember Lucas Hedges as the lead bully in Wes Anderson's "Moonrise Kingdom." The son of director Peter Hedges has since appeared in Jason Reitman's "Labor Day," Terry Gilliam's "The Zero Theorem" and "Kill the Messenger," in which he played Jeremy Renner's son. Here, he plays a teen who falls into the care of his uncle (Casey Affleck) when his father dies. Director Kenneth Lonergan has gotten strong performances out of his young leads in "You Can Count on Me" and "Margaret," and Hedges could be his secret weapon in this film.
Morgan Saylor, "White Girl" - Best known as Dana Brody on "Homeland," Saylor takes center stage in "White Girl," as a college student who goes to extremes to get her drug dealer boyfriend out of jail. It's a potentially explosive role for Saylor, so keep an eye on the rising young actress.
Jacob Latimore, "Sleight" - After holding his own opposite veteran co-stars like Forest Whitaker and Angela Bassett in "Black Nativity," Latimore graduated to supporting roles in box office hits such as "Ride Along" and "The Maze Runner." Now he's in the Sundance spotlight with "Sleight," playing a young street magician who turns to dealing drugs when he's left to care for his little sister following their mother's death. When his sister gets kidnapped, he must rely on his smarts and sleight of hand to save her. If that doesn't sound like a star-making opportunity, what does?
Emma Greenwell, "Love and Friendship" - The "Shameless" star is about to break out in a big way between her supporting role in this Whit Stillman movie and her upcoming turn in "Pride and Prejudice and Zombies." She plays Lady Catherine opposite Kate Beckinsale and Chloe Sevigny in this comic riff on an incomplete Jane Austen novella. Greenwell also co-stars in the upcoming Hulu series "The Path" with Aaron Paul and Michelle Monaghan.
Shashank Arora and the cast of "Brahman Naman" - Controversial Indian filmmaker Q has assembled an intriguing cast for his raunchy sex comedy, which showcases Arora's knack for comedic timing. Arora (in yellow shirt) plays a nerdy, hormone-fueled teen who competes for the National Quiz Championships in 1980s India while trying to lose his virginity along the way.
Lily Gladstone, "Certain Women" - This Native American newcomer is said to hold her own opposite her veteran co-star Kristen Stewart as a reclusive young ranch hand in the throes of her first existential crisis who meets Beth (Stewart), a recent law school grad who teaches an adult education class. Gladstone caught the acting bug after watching a "Star Wars" spinoff and quickly became involved in local theater in Montana, where she grew up on the Blackfeet Indian Reservation. She starred opposite Stewart's "Twilight" co-star Chaske Spencer in "Winter in the Blood" and had a small role in the Benicio del Toro movie "Jimmy P."
Lilith Stangenberg, "Wild" - This up-and-coming German actress plays an young anarchist who chooses a life without hypocrisy or an obligatory safety net. Stangenberg is an unknown entity in the U.S., but seeing as she shares the screen with a wolf, she's guaranteed to have tongues wagging in Park City.