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Jennifer Lopez, Miguel to Appear on 'TRL' in Puerto Rico Relief Effort (Exclusive)

Fat Joe, Victor Cruz and La La Anthony will also appear on Friday's episode

Jennifer Lopez is among the stars helping "TRL" close out its premiere week by focusing on Puerto Rico, TheWrap can exclusively announce.

The recently relaunched series will dedicate Friday's episode to a show of support and solidarity for those affected by the recent hurricanes in the Caribbean.

Lopez, who parents are Puerto Rican, and Miguel will weigh in on the humanitarian crisis in Puerto Rico. (Lopez will appear by phone.)

NFL star Victor Cruz, former MTV VJ La La Anthony, supermodel Joan Smalls and singer Romeo Santos will also guest on the episode.

During Santos' performance, audience members will celebrate Latino heritage with a rainbow of flags and signs adorned with messages of hope.

"TRL" airs weekdays at 3:30/2:30c on MTV.