Julia Roberts, Jennifer Aniston Comedy ‘Mother’s Day’ Acquired by Open Road

After "Leprechaun" (1993), Aniston played Madeline Drego Cooper in the CBS sitcom, "Muddling Through" (1994). 

"Muddling Through" (1994) may have only lasted one season, but 2 weeks after the show wrapped Aniston caught her big break as Rachel Green on NBC's "Friends" (1994-2004). 

Jennifer effortlessly played advertising exec Kate in "Picture Perfect" (1997), pictured here looking perfect with phony fiance Jack (Jay Mohr).   

Her next major flick came in 1997 with the rom-com "The Object of My Affection" opposite Paul Rudd.  

Here's the sassy Jen we know and love telling off her boss in "Office Space" (1999).

"The Good Girl" in 2002 had Jennifer starring as Justine Last, a young woman having an affair with a store clerk (Jake Gyllenhaal) who thinks he's Holden Caulfield.

Aniston hit big screen stride with box office ht "Bruce Almighty" in 2003. The comedy had the actress play the wife to God (or everyman Bruce, played by Jim Carey). 

2004 brought another hit with "Along Came Polly." Jennifer starred as spicy food loving, salsa dancing Polly Prince, pictured here with her pet ferret, Rodolfo. 

In "Friends With Money" (2006), Aniston starred as Olivia, who quits a lucrative job and navigates life surrounded by her wealthy friends. She's pictured here in her first indie flick alongside Frances McDormand.

Aniston starred alongside Owen Wilson in the 2008 tear-jerker "Marley & Me." 

The star had made her name as a great rom-com actress by the release of "He's Just Not That Into You" in 2009. Jen shone amidst an all-star cast that included Scarlett Johansson, Drew Barrymore, and Bradley Cooper to name a few. 

"The Bounty Hunter" (2010) gave Jennifer the chance to flaunt her action movie chops as Nicole Hurley, reporter and ex-wife of Milo Boyd (Gerard Butler) the bounty hunter, on the run from the cops. 

Jen's never strayed far from her comedic roots. Her role as the questionable Dr. Julia Harris, D. D. S. in "Horrible Bosses" (2011) proved dentistry has never looked better. 

Aniston sheds city life for a commune in 2012's "Wanderlust" opposite Paul Rudd. Here, she executes perfect yoga poses alongside fellow commune resident Seth (played by real-life boyfriend Justin Theroux). 

We all know Jennifer Aniston is gorgeous, but she just wanted to remind us with this strip tease scene from "We're The Millers" (2013).

The highly anticipated drama, "Cake" (2014), puts Aniston in an Oscar-worthy role as Claire Bennett, a woman who strikes up a questionable relationship with a widower. The film has reinforced Aniston's status as a true and talented actress. 

Prior to the release of "Cake" (2014), Aniston stopped by TheWrap offices to talk Oscar buzz, and even to get quizzed on, well, Jennifer Aniston.