The actress has come a long way since her days playing Sookie
McCarthy made her feature film debut with a supporting role in "Go," directed by Doug Liman.
"Charlie's Angels: Full Throttle" (2000) The actress had a small role as Doris, a woman flirting with Jimmy Bosley at the crime scene.
"Gilmore Girls" (2000-2007)
McCarthy was cast as Sookie St. James, the best friend of Lorelai Gilmore, in the WB television series. The series ended in 2007, and McCarthy was not asked to return for the reboot announced in February.
McCarthy even earned an Oscar nomination for her role in "Bridesmaids," and presented at the 2012 ceremony with co-star Rose Byrne.
"This Is 40" (2012)
With Paul Rudd and Leslie Mann in the leads of Judd Apatow's comedy, McCarthy played a kid's mom who gets in a verbal argument with Rudd's character, Pete, at school.
"Identity Thief" (2013)
The film was a surprise hit at the box office, debuting to $34.5 million and grossing $134.5 million although it received terrible reviews. Jason Bateman starred in the film about a man getting his identity stolen by a woman.
"The Heat" (2013)
Directed by Paul Feig, McCarthy teamed up with Sandra Bullock to take down a mobster. The film grossed $230 million globally from a $43 million budget.
The film, which received mixed reviews, had McCarthy in the role of a recently-unemployed woman who goes on a road trip with her alcoholic grandmother. The film made $84.5 million domestically.