Charlie Sheen, ‘Two and a Half Men’ Co-Star Jon Cryer to Appear on NBC Special

“Must See TV: A Tribute to James Burrows” will also feature previously announced “Friends” reunion, plus casts of “Frasier,” “Cheers” and more

Charlie Sheen and “Two and a Half Men” co-star Jon Cryer will both appear on NBC’s tribute to James Burrows, the network announced Wednesday.

“Must See TV: A Tribute to James Burrows” will see casts of various iconic TV sitcoms reunite to pay tribute to the prolific director.

As previously announced, most of the cast of “Friends,” including Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc, David Schwimmer – and Matthew Perry in a pre-taped segment, will also be among the star-studded event.

“There is nobody with better TV comedy instincts than Jimmy Burrows, and because of his guiding hand these remarkable shows will be forever celebrated and stand the test of time,” said Paul Telegdy, President, Alternative and Late Night Programming, NBC Entertainment, in a statement. “The caliber of talent joining us to celebrate Jimmy’s accomplishments is a testament to his imprint in television history.”

The special will air Sunday, Feb. 21 at 9 p.m. ET. on NBC.

The full list of participating stars is below, with more to be added.

“Cheers” — Ted Danson, Shelley Long, Bebe Neuwirth, Rhea Perlman, John Ratzenberger, George Wendt (Kirstie Alley, Woody Harrelson in pre-taped segments)

n “Friends” — Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc, David Schwimmer (Matthew Perry in pre-taped segment)

n “Frasier” — Peri Gilpin, Jane Leeves, David Hyde Pierce (Kelsey Grammer in pre-taped segment)

n “Will & Grace” — Sean Hayes, Eric McCormack, Debra Messing, Megan Mullally

n “Taxi” — Tony Danza, Danny DeVito, Marilu Henner, Judd Hirsch, Carol Kane, Christopher Lloyd

n “The Big Bang Theory” — Kaley Cuoco, Johnny Galecki, Simon Helberg, Jim Parsons

n “Wings” — Tony Shalhoub, Steven Weber

n “Mike & Molly” — Billy Gardell, Melissa McCarthy, Katy Mixon, Nyambi Nyambi, Reno Wilson

n “Two and a Half Men” — Jon Cryer, Charlie Sheen

n “Crowded” — Carlease Burke, Stacy Keach, Carrie Preston, Mia Serafino, Patrick Warburton