Summit is adding "50/50" to its release schedule for 2011.
The movie stars Seth Rogen and Joseph Gordon-Levitt and focuses on a young man's struggles with cancer.
Formerly called "I'm With Cancer" and "Live with It," the film -- based on a true story -- will be released wide on September 30.
Despite the heavy subject matter, it's been described as a bittersweet comedy.
Anna Kendrick, Bryce Dallas Howard and Anjelica Huston co-star. Jonathan Levine ("The Wackness") directs.
Summit acquired North American distribution rights in February 2010.
