"Savage Love" sex columnist Dan Savage volunteered on his podcast that on inauguration day, "I am going to be getting high, listening to musicals and sucking a d---. ... I am going to have a media blackout."
Jamie Lee Curtis will also appear during the Love-a-Thon.
Moby says he turned down a DJ gig for the inauguration, and will instead perform at a benefit show on Friday at The Hotel Café in Los Angeles.
Christopher Guest will bring his comedic genius to the "Love-a-Thon."
"Gilmore Girls" actress Kathleen Wilhoite told TheWrap: "I'll be sitting shiva for democracy and equal rights while periodically getting up to go WWE on a punching bag I've colored orange and adorned with tiny doll hands."
John Leguizamo is leading a protest, writing on Twitter: "At noon tomorrow turn your TV's on to anything but the inauguration and lower its ratings as protest to not having a Latinx in his cabinet! ... In solidarity of not 1 Latinx in #trumps cabinet Im asking artists to do a live feed at noon as a protest to #trump at noon time est!"
Oscar winner Patricia Arquette is another "Love-a-Thon" participant.
"Absolutely Fabulous" actress Mo Gaffney told TheWrap: "I'll be in NYC girding my loins, figuratively (and literally because...well Trump and grabbing) to head to the Women’s March on Washington. Plus some mourning of democracy and common decency in the U.S."
Jeff Tweedy of Wilco will provide some "Love-a-Thon" music.
Actor and Academy Award-winning director Fisher Stevens will also join TheWrap and Politico's Inauguration Hub event.