1986 - "Platoon"
In 1986, Sheen starred in the year's Best Picture winner at the Oscars, "Platoon." The movie marked the start of his relationship with director Oliver Stone
Twentieth Century Fox
1987 - "Wall Street"
Sheen starred with his father, Martin Sheen
, in Stone's "Platoon" follow-up, "Wall Street." When Sheen was passed over for Stone's next film, "Born on the Fourth of July" in favor of Tom Cruise
, the actor-director duo had a public falling out.
Twentieth Century Fox
1991 - "Hot Shots!"
Following his work with Stone, Sheen's movie career continued with roles in films including "Young Guns," "Major League" and "Hot Shots!"
1998 - Overdose
In 1998, following several stints in rehab and a public struggle with drug abuse, Sheen suffered a stroke due to an overdose.
2000 - "Spin City"
The actor had a career resurgence on TV in 2000. He replaced Michael J. Fox
as the lead of the ABC series "Spin City" for Seasons 5 and 6.
2002 - Golden Globe
For his role on "Spin City," Sheen walked away with a Golden Globe for Best Actor in a TV Series, Comedy in 2002.
2003 - Two and a Half Men
Following the end of "Spin City," Sheen's TV career continued with Chuck Lorre
's "Two and a Half Men" on CBS in 2003. Sheen starred on the show alongside Jon Cryer for eight seasons.
Aspen Police Department
December 2009 - Domestic Violence Arrest
In 2009, Sheen was arrested in Aspen, Colorado, for second-degree assault, menacing and criminal mischief following a fight with his then-wife Brooke Mueller. He pleaded guilty to a misdemeanor domestic assault charge.
March 2011 - Meltdown
Sheen was fired from "Two and a Half Men" in 2011 after publicly disparaging series creator Chuck Lorre
in an interview. In a string of bizarre interviews and online videos, Sheen launched meme-worthy phrases like "tiger blood" and "winning," as well as lots of head-shaking.
June 2012 - "Anger Management"
Sheen made his TV comeback in 2012 on the FX series "Anger Management," which aired for two seasons and a total of 100 episodes.
November 2015 - HIV announcement
Sheen appeared on the "Today" to announce that he had been diagnosed as HIV-positive four years prior.
Sony Pictures Television
January 2016 - "The Dr. Oz Show"
Sheen said on "The Dr. Oz Show" in early 2016 that he had been off of his HIV medication for "about a week" in favor of alternative treatment in Mexico. "So what? I was born dead," he said.